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Welcome!

The Cancer Discovery Hub (CDH) is a one-stop pan-omics diagnostic and research core laboratory housed at the National Cancer Centre Singapore. We specialise in state-of-the-art research-grade technologies and provide expert support to investigators on all cancer related projects.

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Latest news

Key events and achievements

  • 25 April 2025: Poster Presentations, AACR Annual Meeting, Chicago, USA (Jing Yi Lee, Bavani Kannan)

  • 07 Dec 2024: Poster Presentations, ASH Annual Meeting, New Orleans, USA

  • 11 Oct 2024 : MOU signed with DxD Hub, A*STAR; Collaborative research agreement with PacBio and KITKOJI

  • 14 June 2024 : Poster Presentations, EHA Congress, Madrid, Spain (Boon Yee Lim) 

  • 10 April 2024 : Poster Presentations + Scholar-in-Training Award, AACR Annual Meeting, San Diego, USA (Jing Yi Lee, Tun Kiat Ko)

  • 02 April 2024 : Collaborative research agreement with Illumina

  • 01 Nov 2023: Poster Presentation, CTOS Annual Meeting, Dublin (Elizabeth Lee)​​

  • 15 Sep 2023 : MOU and RCA signed with Agilent Technologies, BioSyngen, BGI Research and MGI Tech

  • 14 June 2023 : Poster Presentation, ICML Lugano, Switzerland​

  • 14 April 2023 : Poster Presentation, AACR Annual Meeting, Florida, USA (Bavani Kannan)​​​​​

  • 20 Mar 2023 : ESMO Merit Award, ESMO Sarcoma and Rare Cancers Congress, Lugano, Switzerland​

  • 18 Mar 2023 : Co-organizer, Singapore Lymphoma Scientific Symposium 2023

  • 12 Dec 2022 : Oral abstract, ASH Annual Meeting, New Orleans, USA​​

  • 09 Dec 2022 : Invited presentation, Stem Cell Society Singapore (SCSS) Symposium (Nimmi Baby)

  • 17 Nov 2022 : Oral paper, CTOS Annual Meeting, Vancouver, Canada (Jing Yi Lee)​

  • 19 Aug 2022 : Invited speech, 6th International BRCA Forum, Singapore​​

  • 19 Aug 2022 : Collaborative research agreement with Scinnohub Pharmaceutical

  • 19 Aug 2022 : Collaborative research agreement with MGI Tech

  • 04 Aug 2022 : Collaborative research agreement with Twist Bioscience

  • 16 Jun 2022 : Best Oral Presentation, International Congress of the Asian Oncology Society (AOS 2022), South Korea (Tun Kiat Ko)​

  • 12 Apr 2022 : Invited Oral Presentation at Major Symposium, AACR Annual Meeting, New Orleans, US

  • 22 Feb 2022 : Publication on circulating tumor DNA mutations in progressive gastrointestinal stromal tumors, Frontiers in Oncology

  • 17 Feb 2022 : Travel Award for Poster abstract at Japanese Society of Medical Oncology Annual Meeting, Japan (Elizabeth Lee)​​

  • ​​12 Jan 2022 : Commercial launch of the UNITED NGS Assay (Lucence) for Asian prevalent cancers at the NCCS

  • 21 Oct 2021 : Collaborative research agreement with STEMCELL Technologies

  • 01 Sep 2021 : Collaborative research agreement with SymBio Pharmaceuticals on EBV-positive lymphomas

  • 01 Sep 2021 : Official launch of Cancer Discovery Hub!

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Featured Publications

Scientific publications supported by the Cancer Discovery Hub

Molecular pathobiology of breast fibroepithelial tumours ESMO Rare Cancers. 2025

Sep, 2025

Breast fibroepithelial tumours are biphasic neoplasms that range from fibroadenomas to varying grades of phyllodes tumours. Although pathological criteria exist to differentiate between these entities, significant intratumoural heterogeneity and histological overlap may complicate diagnosis. In addition, systemic therapy for metastatic cases is ineffective and there is a lack of actionable molecular targets for targeted therapy. In this review, we explore the current understanding of the molecular pathobiology of breast fibroepithelial tumours, and their utility in diagnosis, treatment, and prognosis. We also highlight novel technologies and models that are promising tools in the molecular understanding of breast fibroepithelial lesions and other rare cancers as a whole.

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